What causes Rheumatoid Arthritis?
The causes of rheumatoid arthritis have not been defined as one or the other, but it has been established that it is not communicable. An external aberrant organism might source a primary reaction from the resistance system in the form of altered antibodies. The body doesn’t recognize these altered antibodies as “self”. Also known as rheumatoid factors, these antibodies might mistake the syvonium molecules for an infection. The rheumatoid factor then generates inflammation of the joint lining.
In theory, RA requires susceptibility to the disease through genetic endowment with specific markers such as HLA-DR4/DR1 clusters and an infectious event that triggers an autoimmune response. Though it can be genetically inherited, not all patients of are found to have a history in the family. Moreover it is not necessary that everyone who inherits the gene will also develop the disease.
Recently, scientists have reported that smoking tobacco increases the risk of developing the illness. Research has shown that physical and emotional stress and improper diet are also causal factors for the disease. Environmental factors also seem to play some role in causing rheumatoid arthritis. Food allergies can also act as a trigger.
Regardless of the exact basis, the effect is an immune system prepared to advance inflammation in the joints and sporadically additional tissues of the body. Immune cells, called lymphocytes, are stimulated and chemical envoys (cytokines, such as tumor necrosis factor/TNF and interleukin-1/IL-1) have been detected in the inflamed areas. Find more on the symptoms and diagnosis of Rheumatoid arthritis on Cure Your Arthritis.
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