Rheumatoid arthritis and osteoarthritis - Articular (joints) Arthritis
Aricular (Joints) arthritis is a type of Rheumatoid arthritis and osteoarthritis. Rheumatoid arthritis is commonly polyarticular, i.e. it affects many joints. Apart from inflammation and soft-tissue swelling of many joints at the same time (polyarthritis), the joints are usually affected initially asymmetrically and then progress in an even manner. The pain generally reduces with exercise of the affected joints, but usually they become stiff in the morning for over an hour. The pain in RA is usually worse in the morning in contrast to osteoarthritis where the pain worsens over the day as the joints are used.
Extra-articular manifestations also distinguish this disease from osteoarthritis (hence it is a multisystemic disease). Most RA patients are anemic, either because of the disease itself or gastrointestinal bleeding as a side effect of drugs used in treatment, especially NSAIDs (non-steroidal anti-inflammatory drugs). Hepatosplenomegaly may occur with concurrent leukopaenia (Felty’s syndrome), and lymphocytic infiltration may affect the salivary and lacrimal glands (Sj
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